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Best Sleeping Pills Over The Counter: 8 Effective Options for Restful Sleep

Posted on March 26 2023

In today's fast-paced world, many individuals experience difficulty in achieving restful sleep. If you find yourself struggling to fall or stay asleep, over-the-counter pills may provide a temporary solution. This article explores the best over-the-counter sleeping pills available, offering insights into their effectiveness and potential benefits. Remember, it's always important to consult with a healthcare professional before starting any new medication. 

Before we jump into the world of sleeping pills, let's take a quick detour and check out a revolutionary meditation app called Mesmerize that can help you relax and drift off. 

Introducing the Mesmerize App

Discover a whole new world of tranquility with Mesmerize, your new favorite visual meditation app for finding inner peace and relaxation. 

Mesmerize combines captivating colors and stunning animations with soothing audio to create immersive experiences that allow your mind to unwind. These carefully crafted visual journeys are designed to help you de-stress, refocus, and bring balance to your busy life. 

With a wide range of customizable visual patterns and calming soundscapes, Mesmerize is tailored to your unique preferences, making meditation more enjoyable and accessible than ever before.

Achieve mindfulness, boost your creativity, get better sleep, improve your mental well-being, and more with this easy-to-use app. Whether you're a meditation newbie or a seasoned zen master, Mesmerize offers an engaging, personalized experience for everyone.

Join the growing community of happy users who have found their zen with Mesmerize. Head to the App Store or Google Play to download and unlock a world of tranquility today.

8 Best Sleeping Pills Over The Counter

Stress, anxiety, lifestyle choices, or specific medical conditions can all interfere with our natural sleep patterns, causing irregularities or insomnia. For those seeking a solution, there are over-the-counter pills that often provide an effective solution to your napping struggles. These non-prescription medications can help improve and maintain a regular daily sleep schedule. Let’s take a look at some of them.

1. Diphenhydramine 

Diphenhydramine is a popular antihistamine with an added benefit – it can facilitate better rest! If you're struggling to attain much-needed repose, this medication might be the solution for a peaceful night's slumber. It aids in falling asleep faster and enjoying longer rest durations, leaving you refreshed and prepared to face the day. Keep in mind that it may cause slight grogginess in the morning, so it's best to use it only when necessary, such as during occasional restless nights. Diphenhydramine can be found in pills like Benadryl and Sominex tablets.

While it's not intended for prolonged use or as a solution for ongoing rest issues, it's a useful tool to have on hand for occasional slumber disturbances.

2. Doxylamine Succinate 

Doxylamine succinate is another antihistamine superstar when it comes to helping you get some shut-eye. Like a sleep-inducing champion, it encourages drowsiness and sets the stage for a peaceful night's rest. It's perfect for those times when sleep seems to elude you, but remember, moderation is key! Stick to the suggested dose to keep pesky side effects like dizziness and dry mouth at bay. With doxylamine succinate in your corner, you'll slumber like a baby through the night. You can find properties of doxylamine succinate in over-the-counter pills such as Unisom and Kirkland sleep tablets.

3. Melatonin

Melatonin is a hormone naturally produced and secreted within the human body, playing a vital role in regulating our rest-wake cycles, also known as circadian rhythms. Supplementation with melatonin can offer significant benefits for individuals experiencing disrupted rest patterns, such as those caused by jet lag or shift work rest disorder. These conditions can lead to an imbalance in melatonin production and release, resulting in difficulty falling and staying in a state of rest or adjusting to a new time zone or work schedule.

By taking melatonin supplements, you can effectively signal to your body that it's time for rejuvenating rest, which, over time, promotes a more consistent and regular schedule.

4. Magnesium 

Magnesium is an essential mineral that plays a role in promoting relaxation and reducing insomnia symptoms. Incorporating magnesium supplements into one's daily routine, particularly before bedtime, may be beneficial in achieving a more restful and satisfying sleep experience.

As a vital component of more than 300 enzyme reactions, magnesium plays a significant role in maintaining a balanced internal environment, which in turn influences sleep quality and duration. This mineral exerts its effects through various mechanisms, including the regulation of neurotransmitters and hormones that are directly involved in the sleep process.

5. L-Theanine

L-theanine is an amino acid that is naturally present in green tea as well as some mushrooms and is known for its relaxing and calming properties. It has gained attention for its potential role in improving sleep quality and enhancing a sense of tranquility. One of the notable effects of L-theanine is its ability to increase alpha-brain wave activity. Alpha waves are associated with a state of relaxation and mental alertness. By increasing alpha wave production in the brain, L-theanine before bedtime can induce a state of calmness, improve a relaxed mental state and help reduce sleep latency which is conducive for a good night’s rest.

6. 5-Hydroxytryptophan (5-HTP)

5-HTP, or 5-hydroxytryptophan, is a compound that plays a crucial role in the production of serotonin, a “feel-good” neurotransmitter that is involved in regulating various physiological functions, including sleep. Insufficient levels of serotonin have been associated with insomnia, restless leg syndrome, and certain types of depression.

By increasing serotonin availability in the brain, 5-HTP supplementation can induce a sense of relaxation and support healthy rest patterns. Serotonin also contributes to the synthesis of melatonin, the hormone responsible for sleep regulation. Consequently, elevating serotonin levels through 5-HTP can potentially enhance the body's ability to produce melatonin and improve a good night’s rest.

7. Glycine

Glycine is an amino acid that has been recognized for its beneficial qualities for those nights when you cannot seem to doze off. It plays a significant role in the central nervous system and has been found to have calming effects on the brain. Glycine can be found in leguminous foods such as peas, nuts, and beans, as well as in meat, dairy products, and fish. But, it can also be taken as a synthesized over-the-counter pill.

Glycine's sleep-enhancing effects may be attributed to its impact on body temperature regulation. It has been found to help lower core body temperature, which aids in the onset of rest. This in turn, improves how well you are able to get some rest at night.

8. Acetaminophen

Acetaminophen helps alleviate pain and reduce fever, providing relief for conditions that may interfere with sleep, such as headaches or minor aches and pains. Combined with compounds such as diphenhydramine in over-the-counter pills, it can act as a sedating antihistamine, helping to induce drowsiness. A good example is Tylenol PM pills. By combining these two ingredients, Tylenol PM aims to provide relief from both pain and insomnia.

Alternatives to Sleeping Pills

While non-prescription sleep aids can be helpful in the short term, it's crucial to explore alternative strategies for healthier and more sustainable rest. Here are some alternatives to consider.

1. Herbal Sleep Aids

Combination herbal supplements typically include a blend of various herbs. These supplements provide a synergistic effect for improved sleep. Some recommended herbs include:

  • chamomile tea;
  • passionflower;
  • lemon balm;
  • valerian root.
  1. Sleep Hygiene Practices

Developing a consistent sleep routine, maintaining a comfortable environment, and avoiding stimulants like caffeine and electronics before bed can significantly improve the quality of rest at night. Establishing a relaxing bedtime routine, such as reading a book or taking a warm bath, and setting up your room to feel quiet, dark, and cozy can signal your body to get ready for bedtime. 

2. Cognitive Behavioral Therapy for Insomnia (CBT-I)

CBT-I is a structured therapy that helps identify and modify negative thought patterns and behaviors contributing to insomnia. It focuses on developing healthy rest habits and stress management techniques, providing long-term solutions for improving rest without relying on medication. Working with a therapist can help address underlying issues and develop effective coping strategies for better sleep.

3. Relaxation Techniques 

Practicing relaxation techniques such as deep breathing, meditation, progressive muscle relaxation, and guided imagery can help calm the mind and prepare the body for sleep. These techniques promote relaxation and reduce anxiety, making it easier to fall asleep naturally. Incorporating these techniques into a bedtime routine can signal the body to wind down and promote a more peaceful transition to dreamland.

4. Meditation Apps and Devices

Apps such as Mesmerize can provide guided meditation and healthy rest patterns for a better chance at getting a quality night's rest. These tools can help create a soothing environment, leading to better sleep management. These kinds of apps also offer relaxation techniques, meditation techniques, and calm-inducing sounds that can help relax the mind for a better chance at dozing off into the night.


Non-prescription sleeping pills can provide temporary relief for restless nights. However, this comprehensive guide has uncovered a range of remarkable alternatives as well that can contribute to restful slumber. Among these options, the Mesmerize app stands out as an exceptional tool. It's not just an app; it's a personalized relaxation guide that offers customized meditations to enhance peaceful nights. Consider giving Mesmerize a try—it could be the missing piece in your quest for calming nights and invigorating awakenings. Here's to a future of revitalizing nights and vibrant days!